Articles related to "Tumor Suppressor"
Cancer Basics
A brief, lay description of the evolution of cancer in the body and the terminology necessary.
cells • mutations • genes • hyperplasia • dysplasia
A brief, lay description of the evolution of cancer in the body and the terminology necessary.
cells • mutations • genes • hyperplasia • dysplasia
Cancer Robustness
Robustness is the ability of cancers to adapt to changes in its environment and is a major cause of treatment failures. Viewing cancer as a robust system provides a more logical framework for the development of cancer therapies.
homeostasis • robustness • heterogeneity • feedback-control • multidrug resistance
Robustness is the ability of cancers to adapt to changes in its environment and is a major cause of treatment failures. Viewing cancer as a robust system provides a more logical framework for the development of cancer therapies.
homeostasis • robustness • heterogeneity • feedback-control • multidrug resistance
DNA Mutations Cause Cancer
People do not inherit cancer but instead inherit an increased risk of getting cancer.
cancer • familial cancer • dna mutation • cancer genetics • tumor suppressor
People do not inherit cancer but instead inherit an increased risk of getting cancer.
cancer • familial cancer • dna mutation • cancer genetics • tumor suppressor
Do Tumor-Suppressors Promote Ageing?
The body utilizes tumor-suppressor proteins to inhibit cancer formation. Although this action would seem to increase longevity, and in many cases it does, paradoxically there are situations in which it may accelerate the ageing process.
tumor-suppressors • caretaker • gatekeeper • dna • senescence
The body utilizes tumor-suppressor proteins to inhibit cancer formation. Although this action would seem to increase longevity, and in many cases it does, paradoxically there are situations in which it may accelerate the ageing process.
tumor-suppressors • caretaker • gatekeeper • dna • senescence
Nutrients for the Prevention of Colon Cancer
Although there are many causes of colon cancer, this article focuses on the role of calcium, vitamin D and folic acid in the prevention of this disease.
calcium • receptor protein • protein kinase c • apoptosis • vitamin d
Although there are many causes of colon cancer, this article focuses on the role of calcium, vitamin D and folic acid in the prevention of this disease.
calcium • receptor protein • protein kinase c • apoptosis • vitamin d
The p53 tumor suppressor gene
The p53 gene performs an essential function in its normal role as a tumor suppressor. However, it is found in a mutated form in over half of all types of cancers. A fuller understanding of p53’s activities can lead to novel approaches to cancer treatment.
p53 • tumor suppressor • oncogene • dna • p21 protein
The p53 gene performs an essential function in its normal role as a tumor suppressor. However, it is found in a mutated form in over half of all types of cancers. A fuller understanding of p53’s activities can lead to novel approaches to cancer treatment.
p53 • tumor suppressor • oncogene • dna • p21 protein
Bacterial toxins for the treatment of cancer
The use of live bacteria for the treatment of cancer has a long history, but problems with toxicity have limited its value in medicine. The field has recently been revitalized with the introduction of genetically modified bacteria, as well as the use of isolated toxins and proteins from the bacteria. These bacterial components are being studied individually and in combination with chemotherapeutic drugs in the treatment of cancer.
bacterial toxins • enterotoxins • diarrhea • tumor suppressor • p53
The use of live bacteria for the treatment of cancer has a long history, but problems with toxicity have limited its value in medicine. The field has recently been revitalized with the introduction of genetically modified bacteria, as well as the use of isolated toxins and proteins from the bacteria. These bacterial components are being studied individually and in combination with chemotherapeutic drugs in the treatment of cancer.
bacterial toxins • enterotoxins • diarrhea • tumor suppressor • p53
Cancer Gene Therapy I
Gene therapy is much in the news today. This article describes the principles behind the technology, and the criteria that must be satisfied in order for gene therapy to be successfully applied to the treatment of cancer. One of the major challenges facing the researcher is to find an effective delivery vehicle; therefore, I have presented the most common methods.
gene therapy • oncogene • dna • tumor-suppressor • cell division cycle
Gene therapy is much in the news today. This article describes the principles behind the technology, and the criteria that must be satisfied in order for gene therapy to be successfully applied to the treatment of cancer. One of the major challenges facing the researcher is to find an effective delivery vehicle; therefore, I have presented the most common methods.
gene therapy • oncogene • dna • tumor-suppressor • cell division cycle
Mouse Models in Cancer Research
The use of mouse models is an essential part of the drug development process. Much has been learned about the human cancer condition, and many drugs have been developed to treat cancer through testing with mice. However, the results of mouse studies should be treated with caution, and conclusions not drawn until human clinical trials are completed.
mouse models • genetic engineering • tumor progression • cancer research • human surrogates
The use of mouse models is an essential part of the drug development process. Much has been learned about the human cancer condition, and many drugs have been developed to treat cancer through testing with mice. However, the results of mouse studies should be treated with caution, and conclusions not drawn until human clinical trials are completed.
mouse models • genetic engineering • tumor progression • cancer research • human surrogates