Articles related to "Transcription Factors"

Cells switch from proliferation, a growth phase, to specialization, the active production of proteins, through the process of differentiation.

There is a lot of truth in the old adage "you are what you eat." Nutrigenomics, investigates the interaction between nutrients and genes and how they are manifested.

Oxidative stress occurs when exposure to reactive metabolites (RM) is greater than what our antioxidant enzymes are able to neutralize.

Geneticists have long used genetic switches to turn genes on and off, but until now they have struggled to control the intermediate levels.

To understand how a cell works, you have to take it apart and put it back together. That's the thinking behind synthetic biology.

Broccoli has been labeled as one of nature's superfoods. This article gives a detailed example of nutrigenomics and how eating broccoli can improve our health.

Single nucleotide polymorphisms are minor alterations in the genetic code, but they can result in very important downstream effects on protein function and expression.

Aspirin modifies COX-2 in colon cancer cells and provides anti-tumorigenic effects. Modified COX-2 produces anti-inflammatory lipoxins and resolvins to block cancer.

When a specific type of cell needs a certain protein or other gene product to be synthesized, it can fine-tune the levels of production in a multitude of ways.

Curcumin, a phytonutrient found in turmeric root has many health benefits including antioxidant activity, anti-aging, and immune balancing properties.

Epigenetics, chemical alterations to chromosomes, have been found to be inherited, affecting disease incidence in families and gene expression.

With many positive health benefits (anti-cancer, anti-viral, anti-biotic), drinking Green Tea is the perfect choice when trying to lose weight.

The renin-angiotensin system's involvement in cardiovascular regulation makes it a key target for drugs fighting heart disease.

A newly identified estrogen receptor (ER-beta) is found in prostate cancer cells. Anti-estrogen drugs act via the inflammatory transcription factor NFkappaB.

Inflammation is a healthy defense that becomes a disease risk, if natural reversal is hampered by omega-3 oil deficiency.

Deaths from the Mexican influenza epidemic have the cytokine storm pattern of young, healthy adults. Inflammatory cytokines can be blocked by anti-inflammatory foods.

Curcumin, found in the spice turmeric, is a potent anti-inflammatory agent that reduces physical exhaustion in mice with experimental CFS.

The renin-angiotensin system (RAS) increases blood pressure by activating AT1R, which occurs in numbers determined by its gene expression.

Recognition that the loss of appetite and weight loss associated with cancer is a result of cancer-induced inflammation, may provide therapeutic approaches.

Everyone knows that vitamin D prevents rickets. Increasingly, scientists are learning of its role in regulating immunity and preventing some forms of cancer.

Alpha-lipoic acid is a fatty acid that is found in all cells. It serves several vital functions in oxidative metabolism, but its value as a supplement may be overstated.

Tyrosine kinase signaling is but one path activated by angiotensin II to regulate fluid balance, cell growth, and more.