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Articles related to "P53 Gene"
Detecting Cancer with Autoantibodies constituents. Cancer stimulates autoantibody production due to the presence of unusual proteins or excessive quantities of normal proteins. Due to the great sensitivity of the immune response, researchers are actively engaged in the discovery of autoantibodies as detection tools for cancers. autoantibodies • antigens • antibodies • prostate specific antigen • p53 gene
The p53 tumor suppressor gene The p53 gene performs an essential function in its normal role as a tumor suppressor. However, it is found in a mutated form in over half of all types of cancers. A fuller understanding of p53’s activities can lead to novel approaches to cancer treatment. p53 • tumor suppressor • oncogene • dna • p21 protein
Cancer Gene Therapy II This article concludes an introduction to cancer gene therapy. There are three broad categories for applying gene therapy to cancer treatment: (1)restoring proper gene function, (2)stimulating the body's immune system to destroy the cancer, and (3)introduce a gene that converts an inactive drug into a toxic drug. p53 • p21 • apoptosis • antisense • mutation
Oncolytic Viruses and Cancer Therapy Oncolytic viruses are used to preferentially infect and kill cancer cells, while not harming normal tissues. Recent advances in virology and molecular biology have revitalized the field which now holds great promise. oncolytic • virus • apoptosis • lysis • p53
Apoptosis Apoptosis is programmed cell death in which damaged or defective cells commit suicide for the benefit of the body as a whole. This article provides a description of the process, how it fails to take place in cancer cells, and the latest research aimed in activating apoptosis to treat cancer. apoptosis • bcl-2 • bax • p53 • caspase
Do Tumor-Suppressors Promote Ageing? The body utilizes tumor-suppressor proteins to inhibit cancer formation. Although this action would seem to increase longevity, and in many cases it does, paradoxically there are situations in which it may accelerate the ageing process. tumor-suppressors • caretaker • gatekeeper • dna • senescence
Targeting STAT Proteins for Cancer Therapy Activation of STAT proteins by cancer cells has been shown to be an essential feature of cancer progression. A further understanding of the process can lead to novel methods of cancer therapy. stat proteins • cytokine • tyrosine kinases • p53 • apoptosis |
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