Uncommon ‘Cancer Families’

We have discussed the importance of alterations in various genes to the development of several types of cancer. Among these are several inherited mutations that run in relatively few families. These lead to the familial syndromes like Familial Adenomatous Polyposis involving the mutated APC gene. These mutations, though rare, carry a very high risk of cancer development. For further details read my article on the genetic basis of cancer.

As a result of this increased risk, family members with these mutations must be screened more closely for cancer than the general population. These persons are also more likely to seek out genetic tests to verify their status. Their family history naturally increases the awareness of their cancer risk and dictates that they determine more precisely their individual genetic makeup.

If you are a member of a family with one of these uncommon cancer syndromes, I invite you to share your experience here. This can be a useful avenue to both educate and learn more about your condition. Tell us about your family, what cancer runs in the family, the genetic tests that you have undergone and the type of screening that you are involved in. Perhaps others with similar experiences will share as well in the discussion.

I am hoping that this will develop into a forum for members of ‘cancer families’ with uncommon cancer syndromes. It is good to know that there are others out there that share your diagnosis and even more with other types of syndromes. You can also be sure that others will benefit from your experience.

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