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Back info/ normal vs abnormal disc


© Lynn Seely

Here is information concerning what a normal disc is made of and what the abnormal disc is like. Be sure to read the article on Glucosamine sp you know how to help rebuild your discs!

Biochemical changes associated with the symptomatic human intervertebral disk.

From:

Clinical Orthopaedics & Related Research. [JC:dfy] (293):372-7, 1993 Aug.

Significant changes in disk biochemistry were evident in the nuclei

pulposi of 25 symptomatic disks that demonstrated abnormal diskography.

Compared with the results from ten normal disk from young subjects (mean

age, ten years) and from ten asymptomatic disks from adult patients (mean

age, 33 years), the symptomatic disks demonstrated significantly greater

collagen content than the young and asymptomatic adult subjects,

respectively. Significantly fewer total glycosaminoglycans (GAGs) and

significantly less water content were also evident for the diseased disks.

The mean pH of the nucleus pulposus from 23 patients was also

significantly reduced for the symptomatic disks as compared with the mean

pH measured for four asymptomatic adult subjects. Although significantly

fewer total GAGs were observed for the symptomatic disks, there were no

significant differences in the percent composition of hyaluronic acid

(HA), chondroitin sulfate (CS), or keratan sulfate (KS) among the normal

and symptomatic disks.

Significant changes in disk biochemistry are

associated with the symptomatic disk, and these changes could contribute

to the development of the painful disk syndrome. (or damaged discs/ herniated )

The above information was just to give the reader some background about the disc. Be sure to read the other two reports on Glucosamine and also, does running injure your back.

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