The drawbacks to OPKs are if you are not sure about when ovulation occurs, you are advised to start testing at a certain day in your cycle - for example day 12 - and to test until you see the surge. With me, according to my shortest and longest cycles, I was supposed to start testing on day 10. The first month I tried OPKs I had to buy 2 kits before I finally saw my surge on day 19 and ovulated on day 22. So the guesswork can be very expensive.
Also, the many different brands of OPKs can leave a woman very frustrated. Be sure to read all the instructions. Some brands say that a positive surge is when the result line is as dark as the test line, others say the line has to be darker. OPKs are like pregnancy tests - some can be urinated on directly and others require a cup and dropper. Some kits suggest to use middle-of-the-day urine, while still others require first-morning urine.
See http://www.fertilityplus.org/faq/opk.html for an in-depth look at the many different brands of OPKs.
If you plan on using an OPK, be sure to follow all instructions and to test at the same time every day. Some practitioners suggest to use an OPK every 12 hours, especially if preparing for an inter-uterine insemination. This is because of the fact that the egg sometimes only lives as little as 12 hours. Although OPKs are a good way to tell when
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