Ohio is Where it’s at…Scientifically Speaking


© Diane Stresing

Ohio has gotten a rather bad rap in recent years for losing college grads to other states-not surprisingly, to a lot of warmer climates-and in some literature, it's even been reported as a "brain drain." As a bonafide Buckeye, I don't like hearing that, of course. And looking around the state, I can say that in spite of the trends reported, there are many bright spots of advances and scientific contributions being made right here in Ohio. A few worth noting:

Last year, researchers at Case Western Reserve University School of Medicine (Cleveland) found a new gene that acts like a COX-2 inhibitor and suppresses the growth of colon cancer. The study, in conjunction with researchers from Howard Hughes Medical Institute, was published in the December 14 issue of the Proceedings of the National Academy of Sciences.

Meanwhile, researchers at Ohio State University have found an alternative diabetes treatment. Actually, the researchers merely quantified what some folks knew long ago: the herb Slacia oblonga, native to regions of India and Sri Lanka, decreases insulin and blood glucose levels by 23 -29% -amounts similar to prescription drugs. Read all about it at http://researchnews.osu.edu/archive/salo...

From medical breakthroughs to technology... in January, SmallTimes (which focuses on nanotechnology) proclaimed that Cleveland has made a bid to attract nano-types in a big way.

...And Columbus wangled its way into Popular Science magazine's top 10 cities as ranked by "tech quotient." That is, the city's cumulative rankings as compiled by the editors and experts and academic types in such broad categories as the city residents' level of connectivity (use of cell phones, satellite cable, and HDTV), the city's medical technology (whether GPS is used in emergency response, and the number of clinical trials going on at research hospitals) and the city's "smart use of energy." (Minneapolis was ranked number one-the mayor there drives a hybrid Toyota Prius.)

Ohio Wesleyan University (in Delaware) and Bowling Green University made news for their studies of birds (see Feb '05 issue of National Wildlife). Both of the studies focused on how various bird species' natural adaptations might lead to medical applications in humans. Specifically, how a penguins' diving physiology might be useful in preventing tissue damage in stroke victims (penguins' heart rates drop so low when they dive, they actually don't funnel blood to the extremities-and there is, curiously, no damage to those tissues. The other study considers how some species that migrate thousands of miles beef up for the journey, but then, lose the weight quickly and ironically, don't get fat at any other point in their lives. The genes responsible for that "featherweight" adaptation may lead to answers about, or treatments for, obesity.

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