Indirubin


© David Olle
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References

1. Grandis, J. et.al. Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo. Proc Nat Acad Sci. 2000 Apr 11; 97 (8): 4227-4232.

2. Indirubin. Memorial Sloan-Kettering Cancer Center.

3. Marko, D. et.al. Inhibition of cyclin-dependent kinase 1 (CDK 1) by indirubin derivatives in human tumor cells. Brit J Cancer. 2001; 84 (2): 283-289.

4. Nam, S. et.al. Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells. Proc Natl Acad Sci. 2005 Apr 26; 102 (17): 5998-6003.

5. Turkson, J. et.al. Stat3 activation by Src induces specific gene regulation and is required for cell transformation. Mol Cell Biol. 1998 May; 18 (5): 2545-2552.

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