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Page 3
The major limiting factor in cannabinoid use is their psychoactive effects. Researchers are synthesizing new cannabinoids that could circumvent this problem. Cannabinoids that bind to CB2 or other receptors have already been developed. Clinical trials are taking place in other countries on the use of cannabidiol, since this cannabinoid is less psychoactive. Another possibility would be the development of cannabinoids that do not cross the blood-brain barrier, and thus operate only in the peripheral tissues. Finally, the effectiveness of endocannabinoids could be prolonged if inhibitors of its breakdown could be developed.
1. Guzman, M. Cannabinoids: Potential Anticancer Agents. Nature Reviews Cancer, Vol. 3, No. 10, pp. 745-755 (October 2003) 2. Mandavilli, A. Marijuana Researchers Reach for Pot of Gold. Nature Medicine, Vol. 9, No. 10, p. 1227 (October 2003) 3. Marijuana and Medicine. Institute of Medicine, National Academy of Sciences, 1999.
The copyright of the article Cannabinoids for Cancer Treatment - Page 3 in Cancer Treatment is owned by . Permission to republish Cannabinoids for Cancer Treatment - Page 3 in print or online must be granted by the author in writing.
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