Until a few years ago the only way to save this child was through a bone marrow transplant from a perfectly matched donor, which could only be a brother or a sister or, with lots of luck, a stranger. Perfectly matched means that the recipient and the donor must have the same set of genes that code for proteins whose function has to do with transplant rejection.
Many couples had a second baby hoping for the perfect match, but chances of that happening, except with twins, are very slim; and, besides, remember that the new baby must also be disease-free. In some cases after the mother is pregnant they test the fetus, and if it has the disease the couple chooses to abort it.
It is obvious that parents will do anything possible to save the life of a son. If they already are living through the pain of watching their son die day after day, they probably do not want to go through the whole thing again.
Some parents, of course, decide not to abort and try again. There is a problem with this: the younger the sick baby is the higher the possibilities that the transplant will succeed, because it is healthier. Thus, if the first attempt fails, the parents have to try again immediately, because time is running out and the sick baby is getting sicker.
Now, however, there is a new method that increases the chances of getting the perfect donor. A form of in vitro fertilization (IVF) called pre-implantation genetic diagnosis (PGD), this technology allows researchers to pick an embryo that they know is not only a perfect match but is free of the disease. To do this they take an ovule, fertilize it in vitro, wait until it has divided a few times and then, using genetic engineering techniques, screen it for the genes that indicate the match and do not carry the mutation. Finally, they implant it in the uterus of the mother and soon a healthy baby will be born.
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