You can find some schedule information on the Internet, and no doubt this will increase as time goes on. But, for now, going by bus means a leap of faith. You must have faith that buses go just about everywhere and frequently.
In guide books aimed at independent travelers, you'll probably find addresses of bus terminals, but these change. Note: there might be two or three first-class bus staions within the same town, even in small towns. Ask waiters, taxi drivers, fellow travelers.
Safety is also a concern. Mexican buses get a bad rap stateside, with accounts of attacks, robberies and accidents. However, these are rare when compared to the number of buses and people using them. Incidents happen anywhere you travel, and it makes sense to be careful.
Below are some tips to make your ride smoother and less frustrating.
Maintain a positive attitude. In new and uncertain situations, it's human to be nervous. Oftentimes this personal anxiety results in demanding behavior. The Mexicans are gracious and helpful, but they don't like to be yelled at. Remember, honey catches more flies than vinegar.
Keep a flexible schedule and be open to new experiences. Uno bus line's motto is "Life's a journey, not a destination." Cool, huh? In Mexico, just enjoy the journey, rather than thinking mainly about getting there.
On long hauls, take first-class buses. There are various categories — primera clase, deluxe, executive — and they vary only a few dollars in price. (Note: "Directo" doesn't mean buses don't stop along the way. It merely means the most direct and efficient route is taken, usually with stops only in large towns and cities.) In primera clase, expect air conditioning, television, rest rooms and reclining seats. Executive class may have wider seats and stewards to serve food and beverage.
Don't leave luggage unattended. Most buses, but not all, will give you a baggage ticket. Stay with your luggage until you see it stashed in the compartment under the bus. Overhead storage is small — room for a day pack, not for backpacks or large duffles. Although I encountered no incidents of theft, I heard tales from others of stolen luggage. Stay close to your carry-ons — just as you would anywhere.
