Heart Failure (Part 2)


© Yasser Anathallee

Causes of heart failure.

The most common cause of congestive failure is coronary artery disease--narrowing of the arteries supplying blood to the heart muscle. Although coronary disease often starts at an early age, congestive failure occurs most often in the elderly. Among people more than 70 years old, about 8 out of 1,000 are diagnosed with congestive heart failure each year. The majority of these patients are women, probably because men are more likely to die from coronary artery disease before it progresses to heart failure. Heart failure is also associated with untreated hypertension, alcohol abuse, and drug abuse (primarily cocaine and amphetamines) at any age. Hyperthyroidism and various abnormalities of the heart valves (particularly aortic and mitral) are among the other disorders that can cause heart failure. In addition, viral infection or inflammation of the heart (myocarditis) or primary heart muscle disease (cardiomyopathy), and in rare instances, extreme vitamin deficiencies, can result in heart failure.

Treatment of heart failure.

Whenever possible, the best treatment of congestive heart failure is one of prevention. This includes diagnosing and treating high blood pressure and attempting to prevent atherosclerosis. Other important preventive steps include not smoking, using alcohol in moderation if at all, and abstaining from cocaine and other illicit drugs. A prudent diet, regular exercise, and weight control are also important. When a patient is diagnosed as having heart failure, the first treatment is often restriction of dietary sodium. Drugs may be prescribed as well. Diuretics, available since the 1950s, are often used to help the kidneys get rid of excess water and sodium, thereby reducing blood volume and the heart's workload. Digitalis, a drug that has been used since the 18th century, is still a component of modern therapy. It is prescribed to strengthen the heart's pumping action. Patients taking both diuretics and digitalis may need to supplement their levels of potassium. Newer drugs for the treatment of heart failure include vasodilators, which cause the peripheral arteries to dilate, or open up. This reduces the work of the heart by making it easier for blood to flow. Among the newest vasodilators used for heart failure are the angiotensinconverting enzyme (ACE) inhibitors, which may be used, along with diuretics, in patients with mild-to-moderate or severe congestive failure. ACE inhibitors, which include captopril (Capoten) and enalapril (Vasotec), block the production of a substance called angiotensin II, a potent constrictor of blood vessels. If blood vessels are dilated, the amount of work needed for the heart to pump blood forward is decreased.

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