John Frederick at a young age began to correspond with Luther, beginning in the days when the bull of excommunication was hurled against Luther. He had a vivid interest in the Reformation movement. Not only did John Frederick read Luther's writings, he urged the printing of the first complete (Wittenberg) edition of his works. In his later years John Frederick promoted the compilation of the Jena edition of Luther's Works.
In 1527 John Frederick married Sibylla, the daughter of John III., duke of Cleves. Together they had three sons.
At the age of twenty-one John Frederick succeeded his father as Elector of Saxony, giving him one of seven votes in the Holy Roman Empire. In the beginning he reigned with his stepbrother, John Ernest, but in 1542 became sole ruler.
Politically, John Frederick was aligned with the League of Smalcald, although he tended to be more pacifist. He sought to bring peace between the emperor, Charles V, and his colleagues in the league.
However, events tended to conspire against John Frederick. He surrendered Coburg in 1542 to his brother, John Ernst. And despite seeking peace, the emperor declared war against the league in July 1546. In September John Frederick was placed under the imperial ban. In November Maurice (of Ducal Saxony) invaded the electorate. Hastening from southern Germany, John Frederick drove Maurice from the land and took Maurice's ally, Albert Alcibiades (prince of Bayreuth) prisoner at Rochlitz. John Frederick then overran ducal Saxony, where he was checked by the advance of Charles V.
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