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Medications for Crohn's Disease....Prednisone

© Susan Johnson

What is Prednisone? Prednisone is a synthetic hormone commonly referred to as a "steroid." Pednisone is very similar to the hormone Cortisone, which your own body manufactures. This drug is often referred to as a miracle drug and that it is. It is widely used to treat many illnesses. In Crohn's Disease it is used to reduce the inflammation that occurs in the lining of the intestines.

How does Predinisone work? Prednisone acts in part as an immunosuppressant. "Immune" refers to the immune system. The immune system protests you against foreign bacteria, virus, etc. In some illnesses, the immune system produces antibodies which become overactive and cause undesirable effects. Predinosne suppresses the production of antibodies. This can make it slightly harder for you to fight off infection, but also stabilizes the immune system if it is overactive. Prednisone also works against inflammation to reduce the heat, redness, swelling, and pain.

What are the possible side effects of Prednisone? Side effects do not occur in all patients and are usually related to the amount and length of time Prednisone is used. If you are having any of the side effects listed below you should make you physician aware of it so that he can monitor the length and severity of the side effect.

Weight gain. Prednisone increases your appetite. Follow a diet to maintain your weight. Develop an eating schedule and stick to it. If you eat when you feel hungry, you will be eating all the time.

Susceptible to infections. Prednisone slightly decreases your resistance to infection. Avoid individuals with infectious illnesses if possible. Notify your physician if you develop persistent signs of an infection.

Stomach upset or ulcer. Prednisone may increase acid secretion in your stomach. Take Prednisone with meals, milk or antacids. Do not take on an empty stomach.

Insomnia and mood changes. The cause is uncertain. It is best to take Prednisone at least 3 hours before bedtime. If you are on a daily schedule it is best to take it in the morning.

Hyperglycemia. Prednisone may increase the amount of sugar in your blood to rise. This can be monitored by your physicians with periodic blood work that can be done locally.

Hypertension. Prednisone may cause your blood pressure to rise. This can be treated by your physicians, if necessary.

Fluid retention. Prednisone can cause you to retain fluid. Osteoporosis. Prednisone can make your bones become brittle. This usually occurs after taking Prednisone for a prolonged time. It may

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