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Constance Tom Noguchi - Researcher and Mentor


© Jackie DiGiovanni

Constance Tom Noguchi was born December 8, 1948, in San Francisco. Noguchi developed an interest in biology and physics during high school. She received a B.A. in math and physics from the University of California at Berkeley in 1970, and a Ph.D. in nuclear physics from George Washington University, Washington, DC, in 1975.

Noguchi planned on a career in medicine, but was drawn to physics. After graduation, she received a grant from NIH to do research in the biomedical area and she received training in biology. Her research used a biological perspective and she studied protein chemistry and molecular biology. Her current research involves sickle cell anemia.

Noguchi enjoys many aspects of her work and has benefited from the diversity of her education. During an interview for the Association of Women in Science, she said:

One of the best jobs possible is to be able to do what you enjoy and get paid for it. In research, I have the opportunity to solve problems, to make scientific discoveries, and to share them with colleagues and students in the process. Some solutions can be found using tools ranging from sophisticated electronic equipment and high speed computers to string and wax or pencil and paper. The key is to be able to use your imagination and whatever else is available.

With the continuing changes in the job market and career opportunities, it is important to approach your education as would a wise consumer any product. Explore your options. If you stay focused in a particular area, you will have an easier job of establishing yourself in that one field. The exposure that you experience during your training can always be used to your advantage. 

Dr. Noguchi is currently the Molecular Cell Biology Section Chief at the Laboratory of Chemical Biology, National Institute of Diabetes & Digestive & Kidney Diseases, National Institutes of Health in Bethesda. According to the published research statement, the focus of the section's work is:

The role of cytokines in maintaining stem/progenitor cell characteristics is being investigated. Molecular structure and processing related to cellular function, differentiation, and development are studied using molecular and cell biology, biochemical, and biophysical approaches. Emphasis is on transcriptional regulation and models of proliferation and differentiation including stem cell marking studies and transplantation with particular interest in the function of the erythropoietin receptor and stress response in hematopoietic, neuronal, muscle, endothelial and other stem/progenitor cells. Other studies include differential globin gene expression related to the pathophysiology of sickle cell disease and other hemoglobinopathies.

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The copyright of the article Constance Tom Noguchi - Researcher and Mentor in Biographies of Scientists is owned by Jackie DiGiovanni. Permission to republish Constance Tom Noguchi - Researcher and Mentor in print or online must be granted by the author in writing.

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